Get Flat 10% Off On Anxiety Products !!
Home / Anxiety Medications / Hydrocodone vs. Oxycodone

Hydrocodone vs. Oxycodone

Hydrocodone vs. Oxycodone

Hydrocodone and Oxycodone are considered to be effective pain relivers. Both the medicines are synthesized with the help of opium poppy. Hydrocodone is developed from codeine, while oxycodone is made from an opium alkaloid called thebaine. Both the substances are often prescribed by physicians to treat mild to severe pain. These medications are useful for patients who need pain treatment for a long period.They are usually recommended after other pain drugs have proven ineffective in treating pain.


The medicine impacts central nervous system and blocks the pain signals from going to the brain. The medication can be used as a combination drug or single substance. It is most commonly recommended as a mixture of hydrocodone with acetaminophen. Moreover, it is the active ingredient present in branded painkillers, such as Lortab, Norco and Vicodin.

It can be also combined with Ibuprofen to treat pain and alleviate inflammation and fever. Hydrocodone can be combined with decongestant also. However, it may cause chills, tachycardia, tremor, muscle spasms, and swelling. The hydrocodone effects are similar to heroin that is cheaper and easily accessible. If a person has developed dependence or addiction towards hydrocodone, they turn to heroin as an alternative once their prescription turns out.


The medication changes how the body and brain respond to and sense pain. It is available in both combination and single ingredient medicine. The medicine is the active ingredient in Percocet and OxyContin. This drug often causes seizures, agitation, insomnia, confusion, anxiety, twitching, or loss of strength or energy.

Hydrocodone vs. Oxycodone: Similarities

Both Hydrocodone vs. Oxycodone the substances are labelled as schedule II medicines, meaning they are considered addictive and dangerous, and are thus regulated. A schedule II medication is one step beneath illegal drugs. Both oxycodone and hydrocodone are effective and similar in how they heal pain, but some people think that oxycodone is slightly stronger.

Both the Hydrocodone vs. Oxycodone medicines are very addictive even if you take the correct doses. Most narcotics tend to have similar side effects: vomiting, nausea, sedation, dizziness and lighthedeadness. They both Hydrocodone vs. Oxycodone generate a sense of euphoria that triggers the reward system in brain. Every time this occurs, the brain begins to rewrite itself to seek more of whatever is producing the sense of pleasure.

As they are called opioids, they exaggerate the effects of other drugs that slow the function of brain. For instance, if opioids are combined with muscle relaxants, barbiturates or alcohol, brain function would get slow to such an extent that it could cause difficulty in breathing. Mixing hydrocodone or oxycodone with alcohol is dangerous.

Hydrocodone vs. Oxycodone: Differences

Both the drugs work in same ways. They induce the receptors present in brain to decrease perception of pain and increase pain tolerance. Hydrocodone is an effective instant-release pain reliever when it is mixed with acetaminophen. But when it is recommended by itself, it has a time-release formula. Oxycodone is available in the market both in time-release and immediate form. Keep in mind that hydrocodone has a high probability of producing side effects such as constipation and stomach pain.

Hydrocodone vs. Oxycodone: Effectiveness in Pain Relief

 Both are potent painkillers and have shown to be effective at healing pain. Researchers have found in an emergency situation that the two medicines treat pain equally.Researchers discovered that both the medications were equally effective at healing pain which is caused by fractures.

It was found that the participants felt equal pain relief thirty and sixty minutes after the drug was taken. Those who took hydrocodone experienced constipation frequently than participants who took oxycodone. Another research discovered that the combination of acetaminophen and oxycodone was 1.5 times powerful than hydrocodone and acetaminophen when consumed at equal doses.



A patient should follow their physician’s instructions regarding dose for opioid medicines. The most effective dosage for a painkiller is lowest effective dose that is the minimum potency that keeps an individual’s pain at acceptable level. With the passage of time, a person’s body could adapt to hydrocodone or oxycodone and the initial dose will no longer be productive in controlling pain or discomfort. In such cases, the medic may slowly increase the dose to ensure adequate pain relief.

How to Take Hydrocodone and Oxycodone

A patient should always take these drugs according to their physician’s recommendations. Hydrocodone and oxycodone are available in extended-release capsules, extended-release tablets, concentrated liquids and liquids. Both the medications are also available on the market in combination with other painkillers like aspirin, ibuprofen and acetaminophen.

Generally, an individual consumes extended-release oxycodone dose every twelve hours with food, whereas extended-release hydrocodone is taken once daily, same time every day.

It is important not to soak, chop or crush these medicines. If you want to discontinue these drugs, you should first ask the permission from your healthcare expert. If you stop taking these medications suddenly without doctor’s approval, it can cause withdrawal symptoms.

Leave a Reply

Your email address will not be published.